How to Choose the Right Laboratory Billing Company: What You Should Look For

Many labs agree that lab billing denials are a source of great frustration in the industry, costing $31.50 per claim you submit and resubmit. Worse, up to 65% of denials are never reworked according to the Medical Group Management Association (MGMA).
Beyond its financial impact, lab denials can create administrative burdens, increase staff workload, and lower morale. This led lab managers to adopt a forward-thinking approach by outsourcing their lab billing to a third-party company. But it’s a decision that should not be taken lightly.
In this article, let’s explore what you need to know about choosing the right laboratory billing company for you.
Why should labs outsource their lab billing?
It’s no secret that medical labs are understaffed and highly pressured to process more than 14 billion tests ordered annually. A survey from Siemens Healthineers and The Harris Poll found that lab professionals are experiencing burnout, hindering their ability to maintain high-quality standards for patients.
To address this, outsourcing the lab billing process has become a widely accepted solution, according to Jonathan Clarke, Assistant Professor of Health Policy and Administration at Penn State University:
Over 90% of U.S. hospitals outsource at least one administrative task
Why should labs outsource their lab billing?
And here are the key reasons why they would outsource this function:
1. Extremely complex codes: Labs use a system called Current Procedural Terminology (CPT) codes, wherein each test, panel, and methodology has a specific code. It’s easy to mix them up when your lab staff isn’t well-versed with the codes.
2. Complicated payer-specific rules: Every insurance company has its own set of rules, coverage policies, and preferred codes. You need to always keep your eye out for what one payer covers and what another might deny.
3. Compliance issues and regulatory risk: Medical laboratories in the U.S. must comply with several key federal and state laws for billing, including CMS (Centers for Medicare & Medicaid Services) Audits, Clinical Laboratory Fee Schedule (CLFS), Medicare and Medicaid Program Rules, and Health Insurance Portability and Accountability Act (HIPAA).
4. Overwhelming Denial Management: A significant part of the job is fighting denied or underpaid claims. This requires skilled staff who understand the appeals process.

Proven Laboratory Excellence
Having lab-specific expertise means they don’t just process claims, but also optimizes them.

Proactive Compliance & Advanced Data Security

Operational Efficiency
At its core, lab billing partners should aid the medical lab in performing high-quality tests and delivering accurate results.

A Track Record of Maximizing Reimbursements
Do they have actionable intelligence? This means they provide more than just basic reports, but also offer deep analytics on payer performance, test profitability, and denial trends.
Do they support lab growth? If you want to add complex tests, can the billing partner guide you on the reimbursement landscape, coding requirements, and potential pitfalls before the investment is made?
By applying these standards, your medical lab is empowered to choose a partner dedicated to your financial resilience and commitment to patients.
Find your perfect lab billing fit with Synapse
A diagnostic lab turned to Synapse for help in increasing their average payments. After a year, this lab increased their average monthly collections by 60%.
That’s because Synapse billers have medical backgrounds and extensive training to thoroughly review and match claims to covered diagnoses. We send requests to the laboratory to get a covered diagnosis and respond to insurance requests. The result? A clean claim from the first pass.
Dr. P. N. shares their experience with Synapse and how we made a difference:
“Our office signed on with Synapse over three years ago and we couldn’t be happier with the results and great service we’ve received from them. Our revenues have increased sharply over that period and they have provided valuable assistance with credentialing, compliance and CMS quality activities. With the ever increasing burden of knowledge required to achieve the highest reimbursements, no practice can afford to be without the best practice management support and we definitely have found it in Synapse!”
Elevate your lab’s performance by booking a consultation with us. See what a Synapse partnership can do for you.
Sources:
Arnson, E. (2019, February 28). Practical Tips for Maintaining Control over the Revenue Cycle. HFMA.
https://www.hfma.org/finance-and-business-strategy/63414/
New Survey Reveals Burnout in Clinical Labs Impacts Patient Care, Staff Safety; Optimism that Automation, AI Will Help Tackle Challenges. (2024, July 29). Siemens-Healthineers.com.
https://www.siemens-healthineers.com/en-us/press-room/press-releases/harris-poll-clinical-labs
Probing Question: Is outsourcing of health care services bad? | Penn State University. (2017). Psu.edu.
https://www.psu.edu/news/research/story/probing-question-outsourcing-health-care-services-bad
You might be losing thousands of dollars. (2025, April 3). Mgma.com.
https://www.mgma.com/articles/you-might-be-losing-thousands-of-dollars-per-month-in-unclean-claims